Pubmed papers

2016

Amram N., Hacohen-Kleiman G., Sragovich S., Malishkevich A., Katz J., Touloumi O., Lagoudaki R., Grigoriadis NC., Giladi E., Yeheskel A., Pasmanik-Chor M., Jouroukhin Y., Gozes I.: Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory. Mol Psychiatry. 2016 Jan 19. doi: 10.1038/mp.2015.208.

Poulatsidou KN., Lagoudaki R., Touloumi O., Kesidou E., Boziki M., Ravanidis S., Chlichlia K., Grigoriou M., Grigoriadis N.: Immunophenotype of mouse cerebral hemispheres-derived neural precursor cells. Neurosci Lett. 2016 Jan 12;611:33-9.

2015

Ravanidis S., Poulatsidou KN., Lagoudaki R., Touloumi O., Polyzoidou E., Lourbopoulos A., Nousiopoulou E., Theotokis P., Kesidou E., Tsalikakis D., Karacostas D., Grigoriou M., Chlichlia K., Grigoriadis N.: Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System. Stem Cells Transl Med. 2015 Dec;4(12):1450-62.

Mouzaki A., Rodi M., Dimisianos N., Emmanuil A., Kalavrizioti D., Lagoudaki R., Grigoriadis N.C., Papathanasopoulos P.: Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation. PLoS One. 2015 Aug 28;10(8):e0135434.

Theotokis P., Kleopa K.A., Touloumi O., Lagoudaki R., Lourbopoulos A., Nousiopoulou E., Kesidou E., Poulatsidou K.N., Dardiotis E., Hadjigeorgiou G., Karacostas D., Cifuentes-Diaz C., Irinopoulou T., Grigoriadis N.: Connexin43 and connexin47 alterations after neural precursor cells transplantation in experimental autoimmune encephalomyelitis. Glia. 2015 Oct;63(10):1772-83.

Tsakiri A, Ravanidis S, Lagoudaki R, Poulatsidou KN, Svane IM, Frederiksen JL, Grigoriadis N.: Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis. Acta Neurol Scand. 2015 May;131(5):305-12.

2014

Merenlender-Wagner A, Shemer Z, Touloumi O, Lagoudaki R, Giladi E, Andrieux A, Grigoriadis NC, Gozes I.: New horizons in schizophrenia treatment: autophagy protection is coupled with behavioral improvements in a mouse model of schizophrenia. Autophagy. 2014;10(12):2324-32.

Haider L, Simeonidou C, Steinberger G, Hametner S, Grigoriadis N, Deretzi G, Kovacs GG, Kutzelnigg A, Lassmann H, Frischer JM.: Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron. J Neurol Neurosurg Psychiatry. 2014 Dec;85(12):1386-95.

Lourbopoulos A, Mourouzis I, Karapanayiotides T, Nousiopoulou E, Chatzigeorgiou S, Mavridis T, Kokkinakis I, Touloumi O, Irinopoulou T, Chouliaras K, Pantos C, Karacostas D, Grigoriadis N.: Changes in thyroid hormone receptors after permanent cerebral ischemia in male rats. J Mol Neurosci. 2014 Sep;54(1):78-91.

2013

Gur-Wahnon D1, Mizrachi T, Maaravi-Pinto FY, Lourbopoulos A, Grigoriadis N, Higazi AA, Brenner T.: The plasminogen activator system: involvement in central nervous system inflammation and a potential site for therapeutic intervention. J Neuroinflammation. 2013 Oct 11;10:124.

Rozenstein-Tsalkovich L1, Grigoriadis N, Lourbopoulos A, Nousiopoulou E, Kassis I, Abramsky O, Karussis D, Rosenmann H.: Repeated immunization of mice with phosphorylated-tau peptides causes neuroinflammation. Exp Neurol. 2013 Oct;248:451-6.

Kandinov B1, Grigoriadis NC, Touloumi O, Drory VE, Offen D, Korczyn AD.: Immunohistochemical analysis of sympathetic involvement in the SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):424-33.

Giannakopoulou A, Grigoriadis N, Bekiari C, Lourbopoulos A, Dori I, Tsingotjidou AS, Michaloudi H, Papadopoulos GC.: Acute inflammation alters adult hippocampal neurogenesis in a multiple sclerosis mouse model. J Neurosci Res. 2013 Jul;91(7):890-900.

Katzav A, Grigoriadis NC, Ebert T, Touloumi O, Blank M, Pick CG, Shoenfeld Y, Chapman J.: Coagulopathy triggered autoimmunity: experimental antiphospholipid syndrome in factor V Leiden mice. BMC Med. 2013 Apr 4;11:92.

Xanthopoulos K, Lagoudaki R, Kontana A, Kyratsous C, Panagiotidis C, Grigoriadis N, Yiangou M, Sklaviadis T.: Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism. PLoS One. 2013;8(3):e59143.

Zacharaki D, Lagoudaki R, Touloumi O, Kotta K, Voultsiadou A, Poulatsidou KN, Lourbopoulos A, Hadjigeorgiou G, Dardiotis E, Karacostas D, Grigoriadis N.: Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells isolated from experimental autoimmune encephalomyelitis mice. Mol Neurosci. 2013 Oct;51(2):282-97.

2012

Gold R, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, Tornatore C, Sweetser MT, Yang M, Sheikh SI, Dawson KT; DEFINE Study Investigators. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med. 2012 Sep 20;367(12):1098-107.

Theotokis P, Lourbopoulos A, Touloumi O, Lagoudaki R, Kofidou E, Nousiopoulou E, Poulatsidou KN, Kesidou E, Tascos N, Spandou E, Grigoriadis N. Time course and spatial profile of nogo-a expression in experimental autoimmune encephalomyelitis in C57BL/6 mice. J Neuropathol Exp Neurol. 2012 Oct;71(10):907-20.

Lourbopoulos A, Grigoriadis N. Multimodality in mesenchymal stem cell transplantation highlights the need for stem cell “ethology”. J Neurol Sci. 2012 Sep 15;320(1-2):166-7; author reply 168. Epub 2012 Jun 14. No abstract available.

Kountouras J, Boziki M, Zavos C, Gavalas E, Giartza-Taxidou E, Venizelos I, Deretzi G, Grigoriadis N, Tsiaousi E, Vardaka E. A potential impact of chronic Helicobacter pylori infection on Alzheimer’s disease pathobiology and course. Neurobiol Aging. 2012 Jul;33(7):e3-4. Epub 2012 Feb 9. No abstract available.

Tsakiri A, Kjærsgaard E, Grigoriadis N, Svane IM, Frederiksen JL. Effector and regulatory T cells in patients with acute optic neuritis. Neuroimmunomodulation. 2012;19(2):111-20. Epub 2012 Jan 11.

2011

Levin N, Vaknin-Dembinsky A, Petrou P, Grigoriadis N, Deretzi G, Karussis D. Pseudo-quadriceps sparing in multiple sclerosis. Eur J Neurol. 2011 Sep;18(9):1184-6. doi: 10.1111/j.1468-1331.2010.03331.x. Epub 2011 Feb 8.

Idan-Feldman A, Schirer Y, Polyzoidou E, Touloumi O, Lagoudaki R, Grigoriadis N, Gozes I. Davunetide (NAP) as a preventative treatment for central nervous system complications in a diabetes rat model. Neurobiol Dis. 2011 Dec;44(3):327-39. Epub 2011 Jul 27.

Kappos L, Bates D, Edan G, Eraksoy M, Garcia-Merino A, Grigoriadis N, Hartung HP, Havrdová E, Hillert J, Hohlfeld R, Kremenchutzky M, Lyon-Caen O, Miller A, Pozzilli C, Ravnborg M, Saida T, Sindic C, Vass K, Clifford DB, Hauser S, Major EO, O’Connor PW, Weiner HL, Clanet M, Gold R, Hirsch HH, Radü EW, Sørensen PS, King J. Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring. Lancet Neurol. 2011 Aug;10(8):745-58. Review.

de Sa JC, Airas L, Bartholome E, Grigoriadis N, Mattle H, Oreja-Guevara C, O’Riordan J, Sellebjerg F, Stankoff B, Vass K, Walczak A, Wiendl H, Kieseier BC. Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice. Ther Adv Neurol Disord. 2011 May;4(3):139-68.

Lahiani-Cohen I, Lourbopoulos A, Haber E, Rozenstein-Tsalkovich L, Abramsky O, Grigoriadis N, Rosenmann H. Moderate environmental enrichment mitigates tauopathy in a neurofibrillary tangle mouse model. J Neuropathol Exp Neurol. 2011 Jul;70(7):610-21.

Giannakopoulou A, Grigoriadis N, Polyzoidou E, Touloumi O, Michaloudi E, Papadopoulos GC. Inflammatory changes induced by transplanted neural precursor cells in a multiple sclerosis model. Neuroreport. 2011 Jan 26;22(2):68-72.

Karapanayiotides T, Grigoriadis N. Emboli detection in asymptomatic carotid stenosis. Lancet Neurol. 2010 Oct;9(10):948; author reply 949. No abstract available.

Grigoriadis N, Lourbopoulos A, Lagoudaki R, Frischer JM, Polyzoidou E, Touloumi O, Simeonidou C, Deretzi G, Kountouras J, Spandou E, Kotta K, Karkavelas G, Tascos N, Lassmann H. Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis. Exp Neurol. 2011 Apr 5. [Epub ahead of print] PubMed PMID: 21440544.

Lourbopoulos A, Grigoriadis N, Lagoudaki R, Touloumi O, Polyzoidou E, Mavromatis I, Tascos N, Breuer A, Ovadia H, Karussis D, Shohami E, Mechoulam R, Simeonidou C. Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis. Brain Res. 2011 May 16;1390:126-41. Epub 2011 Mar 13. PubMed PMID: 21406188.

Avraham Y, Grigoriadis N, Poutahidis T, Vorobiev L, Magen I, Ilan Y, Mechoulam R, Berry E. Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. Br J Pharmacol. 2011 Apr;162(7):1650-8. doi: 10.1111/j.1476-5381.2010.01179.x. PubMed PMID: 21182490; PubMed Central PMCID: PMC3057300.

Kountouras J, Zavos C, Deretzi G, Gavalas E, Polyzos S, Katsinelos P, Grigoriadis N, Koutlas E, Rudolf J, Tsiptsios I. Impact of Helicobacter pylori on chronic hepatitis C-related cognitive dysfunction. J Neuroimmunol. 2011 Apr;233(1-2):254-6. Epub 2010 Oct 20. PubMed PMID: 20965574.

2010

Giannakopoulou A, Grigoriadis N, Polyzoidou E, Touloumi O, Michaloudi E, Papadopoulos GC. Inflammatory changes induced by transplanted neural precursor cells in a multiple sclerosis model. Neuroreport. 2010 Dec 10. [Epub ahead of print] PubMed PMID: 21150806.

Karapanayiotides T, Grigoriadis N. Emboli detection in asymptomatic carotid stenosis. Lancet Neurol. 2010 Oct;9(10):948; author reply 949. PubMed PMID: 20864045.

Kountouras J, Boziki M, Gavalas E, Zavos C, Deretzi G, Chatzigeorgiou S, Katsinelos P, Grigoriadis N, Giartza-Taxidou E, Venizelos I. Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients. Cogn Behav Neurol. 2010 Sep;23(3):199-204. PubMed PMID: 20829670.

Deretzi G, Kountouras J, Koutlas E, Zavos C, Polyzos S, Rudolf J, Grigoriadis N, Gavalas E, Boziki M, Tsiptsios I. Familial prevalence of autoimmune disorders in multiple sclerosis in Northern Greece. Mult Scler. 2010 Sep;16(9):1091-101. Epub 2010 Jul 16. PubMed PMID: 20639270.

Boimel M, Grigoriadis N, Lourbopoulos A, Haber E, Abramsky O, Rosenmann H. Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice. Exp Neurol. 2010 Aug;224(2):472-85. Epub 2010 May 28. PubMed PMID: 20546729.

Giannakopoulou A, Grigoriadis N, Polyzoidou E, Lourbopoulos A, Michaloudi E, Papadopoulos GC. Time-dependent fate of transplanted neural precursor cells in experimental autoimmune encephalomyelitis mice. Exp Neurol. 2010 Apr 24. [Epub ahead of print] PubMed PMID: 20420833.

Kountouras J, Gavalas E, Deretzi G, Boziki M, Zavos C, Chatzopoulos D, Katsinelos P, Giartza-Taxidou E, Grigoriadis N, Venizelos I. Helicobacter pylori with or without its neutrophil-activating protein may be the common denominator associated with multiple sclerosis and neuromyelitis optica. Mult Scler. 2010 Mar;16(3):376-7; author reply 378-9. PubMed PMID: 20203152.

2009

Einstein O, Friedman-Levi Y, Grigoriadis N, Ben-Hur T. Transplanted neural precursors enhance host brain-derived myelin regeneration. J Neurosci. 2009 Dec 16;29(50):15694-702. PubMed PMID: 20016084.

Katsara M, Yuriev E, Ramsland PA, Tselios T, Deraos G, Lourbopoulos A, Grigoriadis N, Matsoukas J, Apostolopoulos V. Altered peptide ligands of myelin basic protein ( MBP87-99 ) conjugated to reduced mannan modulate immune responses in mice. Immunology. 2009 Dec;128(4):521-33. PubMed PMID: 19930042; PubMed Central PMCID: PMC2792136.

Lourbopoulos A, Grigoriadis N, Karacostas D, Spandou E, Artemis N, Milonas I, Tascos N, Simeonidou C. Predictable ventricular shift after focal cerebral ischaemia in rats: practical considerations for intraventricular therapeutic interventions. Lab Anim. 2010 Apr;44(2):71-8. Epub 2009 Nov 9. PubMed PMID: 19900985.

Avraham Y, Grigoriadis NC, Magen I, Poutahidis T, Vorobiav L, Zolotarev O, Ilan Y, Mechoulam R, Berry EM. Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice. Br J Pharmacol. 2009 Oct;158(3):896-906. Epub 2009 Sep 18. PubMed PMID: 19764982; PubMed Central PMCID: PMC2765608.

Shein NA, Grigoriadis N, Alexandrovich AG, Simeonidou C, Lourbopoulos A, Polyzoidou E, Trembovler V, Mascagni P, Dinarello CA, Shohami E. Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. FASEB J. 2009 Dec;23(12):4266-75. Epub 2009 Sep 1. PubMed PMID: 19723705; PubMed Central PMCID: PMC2812044.

Kountouras J, Gavalas E, Boziki M, Zavos C, Deretzi G, Grigoriadis N, Tsiaousi E, Katsinelos P, Chatzopoulos D, Tzilves D, Kouklakis G. High prevalence of dementia and cognitive impairment in indigenous Australians. Neurology. 2009 Aug 11;73(6):487; author reply 487-8. PubMed PMID: 19667328.

Salta E, Panagiotidis C, Teliousis K, Petrakis S, Eleftheriadis E, Arapoglou F, Grigoriadis N, Nicolaou A, Kaldrymidou E, Krey G, Sklaviadis T. Evaluation of the possible transmission of BSE and scrapie to gilthead sea bream (Sparus aurata). PLoS One. 2009 Jul 28;4(7):e6175. PubMed PMID: 19636413; PubMed Central PMCID: PMC2712096.

Deretzi G, Kountouras J, Grigoriadis N, Zavos C, Chatzigeorgiou S, Koutlas E, Tsiptsios I. From the “little brain” gastrointestinal infection to the “big brain” neuroinflammation: a proposed fast axonal transport pathway involved in multiple sclerosis. Med Hypotheses. 2009 Nov;73(5):781-7. Epub 2009 May 24. PubMed PMID: 19467574.

Kountouras J, Boziki M, Gavalas E, Zavos C, Deretzi G, Grigoriadis N, Tsolaki M, Chatzopoulos D, Katsinelos P, Tzilves D, Zabouri A, Michailidou I. Increased cerebrospinal fluid Helicobacter pylori antibody in Alzheimer’s disease. Int J Neurosci. 2009;119(6):765-77. PubMed PMID: 19326283.

Shiryaev N, Jouroukhin Y, Giladi E, Polyzoidou E, Grigoriadis NC, Rosenmann H, Gozes I. NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model. Neurobiol Dis. 2009 May;34(2):381-8. Epub 2009 Mar 2. PubMed PMID: 19264130.

Kountouras J, Boziki M, Gavalas E, Zavos C, Grigoriadis N, Deretzi G, Tzilves D, Katsinelos P, Tsolaki M, Chatzopoulos D, Venizelos I. Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer’s disease. J Neurol. 2009 May;256(5):758-67. Epub 2009 Feb 25. PubMed PMID: 19240960.

Boimel M, Grigoriadis N, Lourbopoulos A, Touloumi O, Rosenmann D, Abramsky O, Rosenmann H. Statins reduce the neurofibrillary tangle burden in a mouse model of tauopathy. J Neuropathol Exp Neurol. 2009 Mar;68(3):314-25. PubMed PMID: 19225406.

Kountouras J, Zavos C, Diamantidis MD, Deretzi G, Grigoriadis N, Tsapournas G, Katsinelos P, Molyvas E. A concept of Helicobacterpylori and stress-secreted mast cells’ potential involvement in brain metastases. J Neuroimmunol. 2009 Apr 30;209(1-2):121-2. Epub 2009 Feb 5. PubMed PMID: 19195717.

Irony-Tur-Sinai M, Grigoriadis N, Tsiantoulas D, Touloumi O, Abramsky O, Brenner T. Immunomodulation of EAE by alpha-fetoprotein involves elevation of immune cell apoptosis markers and the transcription factor FoxP3. J Neurol Sci. 2009 Apr 15;279(1-2):80-7. Epub 2009 Jan 25. PubMed PMID: 19171355.

Avraham Y, Zolotarev O, Grigoriadis NC, Poutahidis T, Magen I, Vorobiav L, Zimmer A, Ilan Y, Mechoulam R, Berry EM. Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice. Am J Gastroenterol. 2008 Dec;103(12):3047-56. Erratum in: Am J Gastroenterol. 2009 Mar;104(3):801. Pautahidis, Theofilos [corrected to Poutahidis, Theofilos]. PubMed PMID: 19086956.

2008

Kountouras J, Deretzi G, Grigoriadis N, Zavos C, Boziki M, Gavalas E, Katsinelos P, Tzilves D, Giouleme O, Lazaraki G. Guillain-Barré syndrome. Lancet Neurol. 2008 Dec;7(12):1080-1; author reply 1083-5. PubMed PMID: 19007730.

Shein NA, Grigoriadis N, Horowitz M, Umschwief G, Alexandrovich AG, Simeonidou C, Grigoriadis S, Touloumi O, Shohami E. Microglial involvement in neuroprotection following experimental traumatic brain injury in heat-acclimated mice. Brain Res. 2008 Dec 9;1244:132-41. Epub 2008 Sep 19. PubMed PMID: 18835383.

Kountouras J, Zavos C, Katsinelos P, Grigoriadis N, Deretzi G, Tzilves D. Greek and Israeli patterns of Helicobacter pylori infection and their association with glaucoma: similarities or diversities? J Glaucoma. 2008 Sep;17(6):503-4; author reply 506-7. PubMed PMID: 18794689.

Lourbopoulos A, Karacostas D, Artemis N, Milonas I, Grigoriadis N. Effectiveness of a new modified intraluminal suture for temporary middle cerebral artery occlusion in rats of various weight. J Neurosci Methods. 2008 Aug 30;173(2):225-34. Epub 2008 Jun 28. PubMed PMID: 18634824.

Kassis I, Grigoriadis N, Gowda-Kurkalli B, Mizrachi-Kol R, Ben-Hur T, Slavin S, Abramsky O, Karussis D. Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis. Arch Neurol. 2008 Jun;65(6):753-61. PubMed PMID: 18541795.

Rosenmann H, Grigoriadis N, Eldar-Levy H, Avital A, Rozenstein L, Touloumi O, Behar L, Ben-Hur T, Avraham Y, Berry E, Segal M, Ginzburg I, Abramsky O. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics. Exp Neurol. 2008 Jul;212(1):71-84. Epub 2008 Mar 21. PubMed PMID: 18490011.

Kountouras J, Zavos C, Grigoriadis N, Deretzi G, Katsinelos P, Tzilves D. Helicobacter pylori infection as an environmental familial clustering risk factor for primary open-angle glaucoma. Clin Experiment Ophthalmol. 2008 Apr;36(3):296-7; author reply 297. PubMed PMID: 18412607.

Kountouras J, Zavos C, Grigoriadis N, Deretzi G, Katsinelos P, Tzilves D. Helicobacter pylori infection as a risk factor for primary open-angle glaucoma. ClinExperiment Ophthalmol. 2008 Mar;36(2):196. PubMed PMID: 18352888.

Tanne D, Katzav A, Beilin O, Grigoriadis NC, Blank M, Pick CG, Landenberg P, Shoenfeld Y, Chapman J. Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome. Neurobiol Dis. 2008 Apr;30(1):56-64. Epub 2008 Jan 3. PubMed PMID: 18308578.

Petrakis S, Irinopoulou T, Panagiotidis CH, Engelstein R, Lindstrom J, Orr-Urtreger A, Gabizon R, Grigoriadis N, Sklaviadis T. Cellular prion protein co-localizes with nAChR beta4 subunit in brain and gastrointestinal tract. Eur J Neurosci. 2008 Feb;27(3):612-20. Erratum in: Eur J Neurosci. 2008 Apr;27(8):2212. PubMed PMID: 18279314.

Shein NA, Grigoriadis N, Alexandrovich AG, Simeonidou C, Spandou E, Tsenter  J, Yatsiv I, Horowitz M, Shohami E. Differential neuroprotective properties of endogenous and exogenous erythropoietin in a mouse model of traumatic brain injury. J Neurotrauma. 2008 Feb;25(2):112-23. PubMed PMID: 18260794.

Nadler Y, Alexandrovich A, Grigoriadis N, Hartmann T, Rao KS, Shohami E, Stein R. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury. Glia. 2008 Apr;56(5):552-67. PubMed PMID: 18240300.

2007

Kountouras J, Gavalas E, Boziki M, Zavos C, Deretzi G, Grigoriadis N. Apolipoprotein E polymorphisms in patients with primary open-angle glaucoma. Am J Ophthalmol. 2007 Oct;144(4):638-9; author reply 639. PubMed PMID: 17893016.

Vulih-Shultzman I, Pinhasov A, Mandel S, Grigoriadis N, Touloumi O, Pittel Z, Gozes I. Activity-dependent neuroprotective protein snippet NAP reduces tau hyperphosphorylation and enhances learning in a novel transgenic mouse model. J Pharmacol Exp Ther. 2007 Nov;323(2):438-49. Epub 2007 Aug 24. PubMed PMID: 17720885.

Gavalas E, Kountouras J, Deretzi G, Boziki M, Grigoriadis N, Zavos C, Venizelos I. Helicobacter pylori and multiple sclerosis. J Neuroimmunol. 2007 Aug;188(1-2):187-9; author reply 190. Epub 2007 Jul 5. PubMed PMID: 17614142.

Grigoriadis S, Gomori JM, Grigoriadis N, Cohen JE. Clinically successful late recanalization of basilar artery occlusion in childhood: what are the odds? Case report and review of the literature. J Neurol Sci. 2007 Sep 15;260(1-2):256-60. Epub 2007 May 4. PubMed PMID: 17482211.

Garin T, Rubinstein A, Grigoriadis N, Nedvetzki S, Abramsky O, Mizrachi-Koll R, Hand C, Naor D, Karussis D. CD44 variant DNA vaccination with virtual lymph node ameliorates experimental autoimmune encephalomyelitis through the induction of apoptosis. J Neurol Sci. 2007 Jul 15;258(1-2):17-26. Epub 2007 Mar 23. PubMed PMID: 17382349.

Yaka R, Biegon A, Grigoriadis N, Simeonidou C, Grigoriadis S, Alexandrovich AG, Matzner H, Schumann J, Trembovler V, Tsenter J, Shohami E. D-cycloserine improves functional recovery and reinstates long-term potentiation (LTP) in a mouse model of closed head injury. FASEB J. 2007 Jul;21(9):2033-41. Epub 2007 Mar 9. PubMed PMID: 17351125.

Einstein O, Fainstein N, Vaknin I, Mizrachi-Kol R, Reihartz E, Grigoriadis N, Lavon I, Baniyash M, Lassmann H, Ben-Hur T. Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression. Ann Neurol. 2007 Mar;61(3):209-18. PubMed PMID: 17187374.

Nizri E, Irony-Tur-Sinai M, Grigoriadis N, Abramsky O, Amitai G, Brenner T. Novel approaches to treatment of autoimmune neuroinflammation and lessons for drug development. Pharmacology. 2007;79(1):42-9. Epub 2006 Nov 30. Review. PubMed PMID: 17139193.

2006

Rosenmann H, Grigoriadis N, Karussis D, Boimel M, Touloumi O, Ovadia H, Abramsky O. Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein. Arch Neurol. 2006 Oct;63(10):1459-67. PubMed PMID: 17030663.

Grigoriadis N, Deretzi G, Artemis N, Tascos N, Milonas I. Is there or is there not a place for anti-interferon antibodies in the decision making of multiple sclerosis treatment optimisation? Neurol Sci. 2006 Sep;27 Suppl 5:S355-7. Review. PubMed PMID: 16998719.

Paspaltsis I, Kotta K, Lagoudaki R, Grigoriadis N, Poulios I, Sklaviadis T. Titanium dioxide photocatalytic inactivation of prions. J Gen Virol. 2006 Oct;87(Pt 10):3125-30. PubMed PMID: 16963773.

Kariv-Inbal Z, Ben-Hur T, Grigoriadis NC, Engelstein R, Gabizon R. Urine from scrapie-infected hamsters comprises low levels of prion infectivity. Neurodegener Dis. 2006;3(3):123-8. PubMed PMID: 16954698.

Symeonides PP, Grigoriadis NC, Hatzokos IG. Anterior dislocation of the elbow. J Shoulder Elbow Surg. 2006 Mar-Apr;15(2):249-51. PubMed PMID: 16517374.

Grigoriadis N, Hadjigeorgiou GM. Virus-mediated autoimmunity in Multiple Sclerosis. J Autoimmune Dis. 2006 Feb 19;3:1. PubMed PMID: 16504001; PubMed Central PMCID: PMC1397830.

Einstein O, Grigoriadis N, Mizrachi-Kol R, Reinhartz E, Polyzoidou E, Lavon I, Milonas I, Karussis D, Abramsky O, Ben-Hur T. Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis. Exp Neurol. 2006 Apr;198(2):275-84. Epub 2006 Feb 10. Erratum in: Exp Neurol. 2007 May;205(1):294. PubMed PMID: 16472805.

Moor E, Shohami E, Kanevsky E, Grigoriadis N, Symeonidou C, Kohen R. Impairment of the ability of the injured aged brain in elevating urate and ascorbate. Exp Gerontol. 2006 Mar;41(3):303-11. Epub 2006 Feb 3. PubMed PMID: 16459044.

Irony-Tur-Sinai M, Grigoriadis N, Lourbopoulos A, Pinto-Maaravi F, Abramsky O, Brenner T. Amelioration of autoimmune neuroinflammation by recombinant human alpha-fetoprotein. Exp Neurol. 2006 Mar;198(1):136-44. Epub 2006 Jan 19. PubMed PMID: 16423348.

Karussis D, Grigoriadis S, Polyzoidou E, Grigoriadis N, Slavin S, Abramsky O. Neuroprotection in multiple sclerosis. Clin Neurol Neurosurg. 2006 Mar;108(3):250-4. Epub 2006 Jan 4. Review. PubMed PMID: 16413962.

Grigoriadis N, Grigoriadis S, Polyzoidou E, Milonas I, Karussis D. Neuroinflammation in multiple sclerosis: evidence for autoimmune dysregulation, not simple autoimmune reaction. Clin Neurol Neurosurg. 2006 Mar;108(3):241-4. Epub 2006 Jan 18. Review. PubMed PMID: 16388896.

Einstein O, Ben-Menachem-Tzidon O, Mizrachi-Kol R, Reinhartz E, Grigoriadis N, Ben-Hur T. Survival of neural precursor cells in growth factor-poor environment: implications for transplantation in chronic disease. Glia. 2006 Mar;53(4):449-55. PubMed PMID: 16345032.

Beni SM, Tsenter J, Alexandrovich AG, Galron-Krool N, Barzilai A, Kohen R, Grigoriadis N, Simeonidou C, Shohami E. CuZn-SOD deficiency, rather than overexpression, is associated with enhanced recovery and attenuated activation of NF-kappaB after brain trauma in mice. J Cereb Blood Flow Metab. 2006 Apr;26(4):478-90. PubMed PMID: 16094314.

2005

Yatsiv I, Grigoriadis N, Simeonidou C, Stahel PF, Schmidt OI, Alexandrovitch AG, Tsenter J, Shohami E. Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury. FASEB J. 2005 Oct;19(12):1701-3. Epub 2005 Aug 12. PubMed PMID: 16099948.

Grigoriadis N, Tselios T, Deraos S, Orologas A, Deraos G, Matsoukas J, Mavromatis I, Milonas I. Animal models of central nervous system immune-mediated diseases: therapeutic interventions with bioactive peptides and mimetics. Curr Med Chem. 2005;12(13):1513-9. Review. PubMed PMID: 15974984.

Xanthopoulos K, Paspaltsis I, Apostolidou V, Petrakis S, Siao CJ, Kalpatsanidis A, Grigoriadis N, Tsaftaris A, Tsirka SE, Sklaviadis T. Tissue plasminogen activator in brain tissues infected with transmissible spongiform encephalopathies. Neurobiol Dis. 2005 Nov;20(2):519-27. PubMed PMID: 15922607.

Engelstein R, Grigoriadis N, Greig NH, Ovadia H, Gabizon R. Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time. Neurobiol Dis. 2005 Mar;18(2):282-5. PubMed PMID: 15686956.

Beilin O, Karussis DM, Korczyn AD, Gurwitz D, Aronovich R, Hantai D, Grigoriadis N, Mizrachi-Kol R, Chapman J. Increased thrombin inhibition in experimental autoimmune encephalomyelitis. J Neurosci Res. 2005 Feb 1;79(3):351-9. PubMed PMID: 15605378.

2004

Grigoriadis N, Albani M, Simeonidou C, Guiba-Tziampiri O. Recovery, innervation profile, and contractile properties of reinnervating fast muscles following postnatal nerve crush and administration of L-Dopa. Brain Res Dev Brain Res. 2004 Oct 15;153(1):79-87. PubMed PMID: 15464220.

Grigoriadis N, Ben-Hur T, Karussis D, Milonas I. Axonal damage in multiple sclerosis: a complex issue in a complex disease. Clin Neurol Neurosurg. 2004 Jun;106(3):211-7. Review. PubMed PMID: 15177770.

2003

Papageorgiou A, Trontzos C, Kallistratos H, Kokkas B, Grigoriadis N, Grammaticos P. Slowing growth and histology changes in Lewis lung carcinoma implanted in a partly denervated muscle. Cancer Invest. 2003;21(6):869-72. PubMed PMID: 14735691.

Einstein O, Karussis D, Grigoriadis N, Mizrachi-Kol R, Reinhartz E, Abramsky O, Ben-Hur T. Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis. Mol Cell Neurosci. 2003 Dec;24(4):1074-82. PubMed PMID: 14697670.

Ben-Hur T, Ben-Menachem O, Furer V, Einstein O, Mizrachi-Kol R, Grigoriadis N. Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cells. Mol Cell Neurosci. 2003 Nov;24(3):623-31. PubMed PMID: 14664813.

Karussis D, Michaelson DM, Grigoriadis N, Korezyn AD, Mizrachi-Koll R, Chapman S, Abramsky O, Chapman J. Lack of apolipoprotein-E exacerbates experimental allergic encephalomyelitis. Mult Scler. 2003 Oct;9(5):476-80. PubMed PMID: 14582773.

2002

Grigoriadis N. Interferon beta treatment in relapsing-remitting multiple sclerosis. A review. Clin Neurol Neurosurg. 2002 Jul;104(3):251-8. Review. PubMed PMID: 12127664.

Leker RR, Teichner A, Grigoriadis N, Ovadia H, Brenneman DE, Fridkin M, Giladi E, Romano J, Gozes I. NAP, a femtomolar-acting peptide, protects the brain against ischemic injury by reducing apoptotic death. Stroke. 2002 Apr;33(4):1085-92. PubMed PMID: 11935065.

Albani M, Megalopoulos A, Kiskinis D, Parashos SA, Grigoriadis N, Guiba-Tziampiri O. Morphological, histochemical, and interstitial pressure changes in the tibialis anterior muscle before and after aortofemoral bypass in patients with peripheral arterial occlusive disease. BMC Musculoskelet Disord. 2002;3:8. Epub 2002 Feb 25. PubMed PMID: 11895571; PubMed Central PMCID: PMC89010.

2001

Karussis D, Abramsky O, Grigoriadis N, Chapman J, Mizrachi-Koll R, Niv H, Kloog Y. The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis. J Neuroimmunol. 2001 Nov 1;120(1-2):1-9. PubMed PMID: 11694313.

2000

Kersten P, McLellan DL, Gross-Paju K, Grigoriadis N, Bencivenga R, Beneton C, Charlier M, Ketelaer P, Thompson AJ. A questionnaire assessment of unmet needs for rehabilitation services and resources for people with multiple sclerosis: results of a pilot survey in five European countries. Needs Task group of MARCH (Multiple Sclerosis and Rehabilitation, Care and Health Services Research in Europe). Clin Rehabil. 2000 Feb;14(1):42-9. PubMed PMID: 10688343.

Grigoriadis N, Simeonidou C, Parashos SA, Albani M, Guiba-Tziampiri O. Ontogenetic development of the locomotor response to levodopa in the rat. Pediatr Neurol. 1996 Jan;14(1):41-5. PubMed PMID: 8652014.

Selected Non-PubMed papers

A. Lourbopoulos, S. Grigoriadis, C. Symeonidou, G. Deretzi, N. Taskos, E. Shohami, N. Grigoriadis. Modified Bielschowsky silver impregnation combined with Hematoxylin or Cresyl Violet counterstaining as a potential tool for the simultaneous study of inflammation and axonal injury in the central nervous system. Aristotle University Medical Journal, Feb 2007;34(1):31-39.